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Prerequisites: None. Students may sign up with the Registrar's Office (School of Medicine) to take the course for credit. Auditors (including postdoctoral fellows) are welcome but are requested to register.

Format: West Lecture Hall, Wood Basic Science Building, given 9:00-10:30 a.m. on the dates indicated below. There are seven lectures plus one in-class exam.

Instructor: Jonathan Pevsner (443-923-2686; pevsner@kennedykrieger.org). My office is 400-D Kennedy Krieger.

Computers: You are encouraged to bring a laptop to class (this is optional). Wireless is available.

Readings: One or two published papers will be assigned for each class. PDFs are posted below.

Grading: 50% of grade is based on problem sets (described below), and 50% is based on an in-class, cumulative final exam given Wednesday, January 18.

Problem sets: For each lecture, there will be a take-home, open-book, unlimited time exercise. There are seven problem sets; we will grade you based on your best five scores (thus counting for 50% of your final grade). The exercises are designed for you to go to a computer and apply what you have learned in each lecture (for example, after the BLAST lecture you will do a BLAST search; after the phylogeny lecture you will make a phylogenetic tree). Each problem set will be given out the day of its lecture, and you will typically have one week to complete it.

Teaching assistants: Hugh Cahill (email), Mayra Garcia (email), Jennifer Turney (email).